cognitive decline by employing a multi-compo-
nent lifestyle intervention in at-risk older peo-
ple. Individuals participating in the active arm
of the study received cognitive training, phys-
ical fitness, socialization, nutritional guidance
and monitoring and treatment of medical risk
factors. Participants in the control arm received
only general medical advice.

The results were so noteworthy that two
years later, they made the cover of Scientific
American (April 2017). “A Success in the Fight
Against Alzheimer’s: New Ways to Stop the Fog
of Dementia Before it Starts.” The authors, Miia
Kivipelto and Krister Håkansson, wrote “A
gold-standard clinical trial provides evidence
that diet, exercise and an active social life can
help prevent cognitive decline.”
Medical-science advances when experimen-
tal results are tested by other investigators
and findings are reproduced. The Alzheimer’s
Association recently launched the U.S. Study
to Protect Brain Health Through Lifestyle
Intervention to Reduce Risk (U.S. POINTER)
study. This two-year clinical trial evaluates
whether lifestyle interventions that simultane-
ously target many risk factors protect cognitive
function in older adults who are at increased
risk for cognitive decline.

Dementia has been declared a public health
priority by the World Health Organization.

The WHO 2021 report on dementia stated:
“Studies show that people can reduce their risk Dr. Paul E. Bendheim
of cognitive decline and dementia by being
physically active, not smoking, avoiding harm-
ful use of alcohol, controlling their weight,
eating a healthy diet and maintaining healthy
blood pressure, cholesterol and blood sugar lev-
els. Additional risk factors include depression,
social isolation, low educational attainment,
cognitive inactivity and air pollution.”
As of 2022, approximately 300 trials have
failed to conclusively identify a drug or bio-
logical intervention to prevent or modify the
relentless, progressive course of Alzheimer’s
disease. The only proven approach to slow the
growing epidemic of Alzheimer’s disease is the
management of risk factors, both medical and
lifestyle. This means a personal commitment to
a brain-healthy lifestyle. Each of us has to be our
own brain health quarterback.

One final note: There are numerous causes of
memory problems and dementia, some of which
are treatable and reversible. If you, a loved one,
or a friend are experiencing increasing memory
lapses, forgetfulness or have any concerns about
your brain health, I urge you to speak with a
health care provider. JE
Courtesy of Dr. Paul E. Bendheim
Dr. Paul E. Bendheim is a clinical professor of
neurology at the University of Arizona College
of Medicine – Phoenix and author of “The Brain
Training Revolution: A Proven Workout For
Healthy Brain Aging.” Bendheim is also the
founder, chairman and CEO of BrainSavers, Inc.

Live fully in a
vibrant community
The Quadrangle is an inspired and highly engaged community for older
adults. Here, you will join residents who are as creative, active, and
intellectual as you. Plus, you’ll get to know our in-house chef who crafts
fresh, seasonal dishes made with your tastes in mind.

Join us for lunch to meet our welcoming residents
and sample our cuisine for yourself.

Get in touch by calling 610-484-4328 or visiting TheQuadrangleCCRC.com/Exponent.

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