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Comment: 10/8 Cancer Awareness Section
FIGHTING CANCER
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Dr. Naama Geva-Zatorsky of the Technion Integrated Cancer Center in Haifa is among a growing number of
cancer researchers studying bacteria that live in the gut microbiome.

Courtesy of the Technion via JTA.org
ecosystems that are known to
contain immune cells, stromal
cells, blood vessels, nerves and
many more components in
addition to cancer cells. Th ey’re
all part of what’s known as the
tumor microenvironment.

“Our studies, as well as
studies by other labs, clearly
demonstrate that bacteria are
also an integral part of the
tumor microenvironment,”
Straussman said. “We hope
that by fi nding out how exactly
they fi t into the general tumor
ecology, we can fi gure out novel
ways of treating cancer.”
Supervising a 10-person lab,
she has tested at least 60 types
of bacteria that thrive in the
human gastrointestinal tract.

Geva-Zatorsky hopes to learn
whether the immune eff ects of
gut bacteria can be used either
to prevent cancer from forming
or to increase the effi cacy of
cancer treatments.

“We believe we can induce
an environment where cancer
cannot develop,” she said.

“Maybe in the future bacteria
that stimulate the immune
system can be added to immune
therapy, so that the cancer can
be eradicated more quickly and
effi ciently.”
Her work, too, is being
funded by the Israel Cancer
Research Fund.

“We’ve known for centuries
that the bacteria in your gut
play important roles, but in the
last three to fi ve years it’s been
discovered that a collection of
bacteria infl uences your immune
response,” Israel said. “Th at’s
important now because of the
major new modalities of treatment
that modify the immune system
to fi ght off the tumor.” ●
This article was sponsored by and
produced in partnership with the
Israel Cancer Research Fund.

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Dr. Ravid Straussman of the Weizmann Institute of Science found that bacteria living inside cancer cells are likely
to have a profound eff ect on how diff erent types of tumors behave.

Photo by Larry Luxner via JTA.org
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